Not known Facts About phenobarbital sodium injection dailymed
Not known Facts About phenobarbital sodium injection dailymed
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pentobarbital will reduce the level or effect of ziprasidone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will reduce the extent or effect of sunitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will increase toxicity of methoxyflurane by expanding metabolism. Contraindicated. Elevated metabolism of methoxyflurane to nephrotoxic compounds.
pentobarbital will reduce the level or effect of prednisone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
buprenorphine transdermal and pentobarbital equally improve sedation. Avoid or Use Alternate Drug. Restrict use to individuals for whom alternative therapy solutions are inadequate
pentobarbital will lessen the level or effect of ethinylestradiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. The efficacy of hormonal contraceptives can be lowered. Usage of a nonhormonal contraceptive is recommended.
pentobarbital will lessen the level or effect of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to your decrease in fentanyl plasma concentrations, not enough efficacy or, possibly, improvement of the withdrawal syndrome inside of a patient who has formulated physical dependence to fentanyl.
pentobarbital will lessen the extent or effect of etravirine click here by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the extent or effect of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with strong CYP3A4 inducers may end up in lessened serum concentrations and lack of antimalarial efficacy
Use in pregnancy: Barbiturates can result in fetal destruction when administered to the Expecting lady. Retrospective, situation-controlled research have recommended a relationship concerning the maternal consumption of barbiturates and a better than expected incidence of fetal abnormalities. Following oral or parenteral administration, barbiturates quickly cross the placental barrier and they are dispersed all through fetal tissues with highest concentrations located in the placenta, fetal liver, and brain.
pentobarbital will lower the extent or effect of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or effect of tipranavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will lessen the level or effect of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir could be lessened if coadministered with sturdy CYP3A inducers and it is consequently contraindicated.
pentobarbital will minimize the extent or effect of capivasertib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Powerful or moderate CYP3A inducers minimize capivasertib publicity, which may decrease efficacy.